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Hydrogen peroxide (H2O2) is an important product of oxidative metabolism that is key to the killing of microorganisms, it can damage DNA, protein and lipid membranes and may even be a causative factor of cancer. It is formed from superoxide anion and can be converted into a highly bactericidal hypohalous (usually hypochlorous) acid by the lysosomal enzyme, myeloperoxidase. Hydrogen peroxide can also be reduced further, to form the potent oxidant, hydroxyl radical. Hydrogen peroxide is broken down by catalase if it is not utilized as described above. ... Increasing the temperature alters the 3D shape and so the enzyme can no longer fit the substrate. ...
What affect does catalase have?
· Catalase is a very fast reacting enzyme; it is found in many living cells, it breaks down hydrogen peroxide to water and oxygen. In fact one molecule of it can deal with six million molecules of hydrogen peroxide in 1 minute. Hydrogen peroxide is toxic so needs to be changed into harmless substances. ... If the active site is altered the substrate will no longer fit in and so the enzyme doesn’t work properly.
Approximate Word count = 821
Approximate Pages = 3.3
(250 words per page double spaced)
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