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The peroxisome is an organelle found in most eukaryotic cells. Its main objective is to oxidise organic molecules, mostly fatty acids, and turn them into hydrogen peroxide, and is also involved in the synthesis of bile acid, cholesterol, and others. The gene which produces peroxisome is the Peroxisome Proliferator Activated Receptor, or PPAR in short. There are 3 isotypes of PPAR: alpha, beta(delta) and gamma. Each type of PPAR has its speciality. PPAR alpha and gamma control energy homoeostasis and inflammatory responses. PPAR beta has been recently discovered to be implicated in skin wound healing. Dr Andrew Tan’s talk focused on the PPAR beta in repairing skin wounds. Their main test subjects were mice. They soon developed knockout mice, which are mice without PPAR beta. These mice grew up to be obese, thrice as much as normal mice. Fat accumulated tremendously without the presence of PPAR beta.
Approximate Word count = 556
Approximate Pages = 2.2
(250 words per page double spaced)
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