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Growth Cones
Definition
• A specialised region at the tip of a growing neurite that is responsible for sensing the local environment and moving toward the neurons target cell.
• Growth cones are hand shaped, with several long filopodia that differentially adhere to surfaces.
• Growth cones can be sensitive to several guidance cues, for example: surface adhesiveness, growth factors, neurotransmitters and electric fields. ...
• Based on these processes, it seems that growing axons are able to sense attractive or repellent materials, and to orient their growth accordingly. The growing tips of axons are enlarged into more or less conical regions called "growth cones."
• Growth cones are highly motile structures that extend and retract fine tubes of cytoplasm and membrane called filopodia. The axon elongates as the growth cone moves forward, and new plasma membrane is added into the growth cone.
Approximate Word count = 625
Approximate Pages = 2.5
(250 words per page double spaced)
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